Background: Implant patients with congenitally missing teeth share some common charateristics and deserve\nspecial attention.\nMethods: The PICO question was ââ?¬Å?In patients with congenitally missing teeth, does an early occlusal rehabilitation\nwith dental implants in comparison to tooth autotransplants, conventional prosthetics on teeth or preservation of\ndeciduous teeth have better general outcomes in terms of survival, success and better patient centered outcomes\nin terms of quality of life, self-esteem, satisfaction, chewing function?ââ?¬Â\nAfter electronic database search, a total of 63 relevant studies were eligible, of which 42 qualified for numerical data\nsynthesis, 26 being retrospective studies. A data synthesis was performed by weighted means for survival/success/\nannual failure rates.\nResults: The mean survival of implants was 95.3 % (prosthesis survival 97.8 %), autotransplants 94.4 %, deciduous teeth\n89.6 %, and conventional prostheses 60.2 %. The implant survival in children, adolescents, and adults was 72.4, 93.0, and\n97.4 %. Annual failure rates of implants 3.317 %, autotransplants 1.061 %, deciduous teeth 0.908 %, and conventional\nprostheses 5.144 % indicated better results for natural teeth and more maintenance needs for the both prosthetic\ntreatments. The mean OHIP score was 27.8 at baseline and a mean improvement of 14.9 score points was reported after\nimplant prosthetics. The mean satisfaction rates were 93.4 (implants), 76.6 (conventional prostheses), 72.0\n(autotransplants), and 65.5 % (orthodontic space closure).\nConclusions: In synopsis of general and patient-centered outcomes, implants yielded the best results,\nhowever, not in children <13 years. Autotransplants and deciduous teeth had low annual failure rates and are\nappropriate treatments in children and adolescents at low costs. Conventional prosthetics had lower survival/\nsuccess rates than the other options. Due to heterogeneity and low number of studies, patient-reported\noutcomes in this review have to be interpreted with caution.
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